Lee-Yung Shih Selected Research

Myeloid Sarcoma (Chloroma)

1/2022	Hoxa11-mediated reduction of cell migration contributes to myeloid sarcoma formation induced by cooperation of MLL/AF10 with activating KRAS mutation in a mouse transplantation model: Hoxa11 in myeloid sarcoma formation.
10/2013	Involvement of Gpr125 in the myeloid sarcoma formation induced by cooperating MLL/AF10(OM-LZ) and oncogenic KRAS in a mouse bone marrow transplantation model.

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Lee-Yung Shih Research Topics

Disease

20	Neoplasms (Cancer) 10/2020 - 08/2003
12	Leukemia 07/2021 - 09/2008
10	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2021 - 01/2003
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2020 - 03/2005
5	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 10/2019 - 07/2003
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 10/2020 - 09/2004
4	Hemorrhage 04/2015 - 09/2009
4	Lymphoma (Lymphomas) 07/2011 - 01/2006
3	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2020 - 01/2010
2	Myeloid Sarcoma (Chloroma) 01/2022 - 10/2013
2	Disease Progression 07/2021 - 01/2013
2	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2020 - 01/2018
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020 - 09/2014
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2019 - 01/2019
2	Splenomegaly 12/2018 - 07/2015
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 04/2015 - 06/2014
2	Thrombosis (Thrombus) 01/2013 - 01/2013
2	Disseminated Intravascular Coagulation 01/2013 - 04/2012
2	Polycythemia Vera 11/2011 - 10/2009
2	Myeloid Leukemia (Leukemia, Myelocytic) 04/2010 - 03/2005
2	Hematologic Neoplasms (Hematological Malignancy) 01/2010 - 01/2006
2	Acute Promyelocytic Leukemia 09/2009 - 09/2003
2	Tumor Lysis Syndrome 09/2008 - 01/2006
1	Acute Erythroblastic Leukemia (Erythroleukemia) 01/2022
1	Residual Neoplasm 10/2021
1	Leukocytosis (Pleocytosis) 02/2020
1	Inflammation (Inflammations) 01/2020
1	Epstein-Barr Virus Infections 01/2020
1	Blast Crisis (Blast Phase) 10/2019
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 09/2019
1	Hyperplasia 12/2018
1	Carcinoid Tumor (Carcinoid) 06/2017
1	Gastric Outlet Obstruction 06/2017
1	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 08/2016
1	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 08/2015
1	Primary Myelofibrosis (Myelosclerosis) 07/2015
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 04/2015
1	Thrombocytopenia (Thrombopenia) 04/2015
1	Ascites 06/2014
1	Myocardial Infarction 01/2013
1	Ischemic Stroke 01/2013
1	Cerebral Infarction 01/2013
1	Acute Megakaryoblastic Leukemia (Leukemia, Megakaryocytic) 11/2012

Drug/Important Bio-Agent (IBA)

6	Biological ProductsIBA 10/2020 - 09/2005
6	Proteins (Proteins, Gene)FDA Link 10/2020 - 07/2003
4	Rituximab (Mabthera)FDA Link 01/2018 - 01/2010
3	Transcription Factors (Transcription Factor)IBA 10/2019 - 01/2017
2	ruxolitinibIBA 01/2022 - 07/2015
2	Immunoglobulins (Immunoglobulin)IBA 10/2021 - 06/2014
2	Cytarabine (Cytosar-U)FDA LinkGeneric 07/2021 - 03/2017
2	DNA Methyltransferase 3AIBA 02/2020 - 11/2018
2	CytokinesIBA 01/2019 - 08/2009
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2019 - 03/2017
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 01/2009
2	Vincristine (Oncovin)FDA LinkGeneric 01/2018 - 02/2002
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2018 - 02/2002
2	Tyrosine Kinase InhibitorsIBA 01/2013 - 09/2008
2	Imatinib Mesylate (Gleevec)FDA Link 01/2013 - 09/2008
2	Fibrinogen (Factor I)FDA Link 01/2013 - 04/2012
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 04/2012 - 09/2009
2	Dacarbazine (DIC)FDA LinkGeneric 04/2012 - 01/2009
2	Erythropoietin FDA Link 10/2009 - 08/2003
2	Dexamethasone (Maxidex)FDA LinkGeneric 09/2009 - 06/2008
2	fms-Like Tyrosine Kinase 3IBA 09/2004 - 09/2003
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 07/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Dihydrotachysterol (AT 10)IBA 02/2020
1	Histone-Lysine N-MethyltransferaseIBA 02/2020
1	HLA-DPB1 antigen (HLA DPB1)IBA 01/2020
1	Cyclin D3IBA 01/2020
1	Cyclin D1IBA 01/2020
1	CyclinsIBA 01/2020
1	Cyclin D2IBA 01/2020
1	HLA-DRB1 Chains (HLA DRB1)IBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2019
1	Interleukin-5 Receptors (Interleukin 5 Receptor)IBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2019
1	Bortezomib (Velcade)FDA Link 01/2018
1	Prednisone (Sone)FDA LinkGeneric 01/2018
1	A 7 (A-7)IBA 06/2017
1	AntralIBA 06/2017
1	Immunosuppressive Agents (Immunosuppressants)IBA 06/2017
1	Daunorubicin (Cerubidine)FDA LinkGeneric 03/2017
1	Janus Kinase 1IBA 07/2015
1	Janus Kinase InhibitorsIBA 07/2015
1	Inosine Triphosphate (ITP)IBA 04/2015
1	eltrombopag FDA Link 04/2015
1	Monoclonal AntibodiesIBA 09/2014
1	CohesinsIBA 10/2013
1	Adenosine Diphosphate (ADP)IBA 01/2013

Therapy/Procedure

11	Therapeutics 02/2020 - 06/2008
7	Drug Therapy (Chemotherapy) 08/2016 - 02/2002
4	Transplantation 01/2022 - 04/2010
4	Bone Marrow Transplantation (Transplantation, Bone Marrow) 02/2020 - 01/2003
2	Aftercare (After-Treatment) 01/2017 - 04/2015
1	Liver Transplantation 09/2019
1	Organ Transplantation 09/2019
1	Hematopoietic Stem Cell Transplantation 06/2017
1	Laparotomy 06/2014
1	Catheters 01/2013